Direct exchange blood transfusion in treatment of hepatic coma.

Treatment of hepatic coma by exchange blood transfusion.

Hepatic coma with renal failure, treated by repeated exchange transfusion.

Hepatic coma following acute hepatic necrosis carries a high mortality in spite of conventional therapy (Katz et al., 1962; McDonald and De la Harpe, 1963; Cook and Sherlock, 1965), but the concomitant development of renal failure makes the prognosis even worse (Hecker and Sherlock, 1956). Owing to the extraordinary capacity of the liver to regenerate, other forms of treatment have recently bee...

treatment of hepatic coma by exchange transfusion : a report of three cases

three cases of hepatic coma due to acute hepatitis were treated by exchange transfusion with citrated blood. this was preformed in the first 2 cases (patients no 1 and no 2) after failing to respond to other forms of treatment, and in the last patient, who was admitted to hospital in coma, a few hours after admission. (patient no 3) two of the 3 patients, patients 1 and 3 recovered, 1 died, (pa...

Alterations in blood pressure during exchange transfusion.

Blood pressure changes as a function of the rates of blood withdrawal and infusion were determined during exchange blood transfusion in 2 preterm newborn infants. 10 ml blood withdrawal and infusion completed within 3 minutes resulted in reversible changes in aortic pressure, whereas the same procedure completed within 45 to 60 seconds resulted in a progressive fall in the systolic pressure and...

Neonatal paracetamol poisoning: treatment by exchange transfusion.

The metabolism and excretion of paracetamol was studied in an infant of 29 weeks' gestation who was exposed to the drug when his mother ingested 32.5 g 16 hours before delivery. We have confirmed that sulphation is the major pathway and that the mixed function oxidase system is sufficiently active at this gestational age to produce hepatotoxic metabolic products. As most of the recognised drug ...